New North Carolina State University research shows that key proteins known for their ability to prevent viral infections by inducing cell death can also block certain bacterial infections without triggering the death of the host cells.

Rather than killing host cells infected by Listeria in the gastrointestinal tract, the RIPK3 and MLKL proteins recognize the chemical composition of the bacteria and MLKL binds to it, preventing the spread of Listeria while keeping the host cells alive.While we've shown that these proteins take on a different function in intestinal epithelial cells than they do in immune cells, we're still not sure how or why this differentiation occurs.

2nd World Congress on Cell and Structural Biology

December 2-3, 2019 Manila, Philippines

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